Citation
(2007), "Nitrosamine analysis", Nutrition & Food Science, Vol. 37 No. 5. https://doi.org/10.1108/nfs.2007.01737eab.011
Publisher
:Emerald Group Publishing Limited
Copyright © 2007, Emerald Group Publishing Limited
Nitrosamine analysis
Nitrosamine analysis
MIP Technologies and Supelco launched a new selective solid phase extraction (SPE) product for analysis of tobacco-specific nitrosamines (TSNAs).
Fast and cost-effective molecularly imprinted polymer technique has applications in testing of TSNAs in urine.
Lund, Sweden, 22 May 2007 – MIP Technologies AB and Supelco, a division of Sigma-Aldrich (NASDAQ: SIAL), a leading USD 1.7 billion Life Science and High Technology company, announced today the launch of a new SPE product for the selective extraction of TSNAs.
The SupelMIPTM TSNA cartridge is selective for the TSNAs: NNN, NNK, NAT, NAB. TSNAs are a class of known carcinogens that are found only in tobacco products. The TSNAs are created during fermentation, curing and burning of the tobacco leaf. Exposure to TSNAs from tobacco products can be confirmed by their detection in, e.g. urine.
Conventional methods used for sample preparation of TSNAs are very elaborate and time-consuming. Extraction with the new TSNA SupelMIPTM is fast and cost effective and the total sample pre-treatment time is less than two hours.
The method is robust, recoveries achieved are higher than 90 per cent and the clean extracts allow low-detection levels with minimized matrix effects.
The SPE sorbents based on molecularly imprinted polymers (MIPs) have been developed by MIP Technologies. SupelMIPTM is a trade mark of Supelco, which distributes the product worldwide.
"As the release of SPE products continues for difficult targets, we expect to establish molecular imprinting as the method of choice for such applications", said Dr Christine Widstrand, VP Sales & Marketing at MIP Technologies. "The high recoveries, speed and ease of extraction and elimination of traditional, labor-intensive extraction steps are hallmarks of the SupelMIPTM product family.
"With molecularly imprinted polymer technology, analysts can reach a level of sample prep extraction selectivity that could not be achieved by conventional means", said An Trinh, Product Manager, Supelco. "With the widespread advent of mass spec technology, more and more methods are requiring lower limits of quantitation when analyzing difficult and dirty sample matrices. Improvements in selectivity during sample preparation is absolutely critical. By merging the strengths of both organisations in this collaborative effort, a new generation of innovative MIPs and applications will emerge".
About MIP Technologies
MIP Technologies AB is a world leading company in the development of MIPs. The Company is a pioneer in the commercial applications of MIPs, holds important patents and maintains cutting-edge research activities in the area. The Company's mission is to provide innovative products based on MIPs that serve industry's needs in analytical, preparative and process scale "selective separations". The Company has environmental permission to produce MIP phases at the 500kg level and is well placed to develop large-scale separation solutions for its customers. Currently the Company develops analytical separation products (e.g. SPE) and has multiple custom process scale projects in place with several blue chip companies. MIP Technologies has its headquarters in Lund, Sweden.
For more information about MIP Technologies AB visit www.miptechnologies.com