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Effect of meal timing and frequency on lipid profile in adults: an overview of systematic reviews and meta-analyses

Alene Sze Jing Yong (School of Pharmacy, Monash University Malaysia, Subang Jaya, Malaysia)
Rosamund Wei Xin Koo (School of Pharmacy, Monash University Malaysia, Subang Jaya, Malaysia)
Choon Ming Ng (School of Pharmacy, Monash University Malaysia, Subang Jaya, Malaysia)
Shaun Wen Huey Lee (School of Pharmacy, Monash University Malaysia, Subang Jaya, Malaysia)
Siew Li Teoh (School of Pharmacy, Monash University Malaysia, Subang Jaya, Malaysia)

Nutrition & Food Science

ISSN: 0034-6659

Article publication date: 14 June 2024

Issue publication date: 2 July 2024

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Abstract

Purpose

Dyslipidaemia is an established risk factor for cardiovascular diseases. Calorie restriction and adopting a heart-healthy diet like the Mediterranean diet are the main dietary interventions for dyslipidaemia. Other dietary behaviours, such as changes in meal frequency and timing, are not included in the major dietary advice guidelines despite the potential correlation between eating patterns and lipid metabolism. This overview of systematic reviews and meta-analyses aims to summarise the effect of meal timing and frequency on lipid profile and make possible recommendations on which meal timing pattern is superior in reducing lipid levels.

Design/methodology/approach

According to the protocol published on PROSPERO (CRD42021248956), five databases were searched for systematic reviews and meta-analyses investigating the effects of meal timing and frequency on lipid profile in adults.

Findings

Five reviews were included, with two reviews on breakfast skipping and meal frequency, respectively, and one review on night-time eating. Increasing meal frequency while maintaining the total calorie intake was reported to reduce total cholesterol and low-density lipoprotein (LDL) levels with low- to moderate-quality evidence. There was a correlation between breakfast skipping and an undesirable increase in LDL levels with low-quality evidence. However, there needs to be more high-quality evidence to conclude the effect of dietary behaviours on blood lipid levels.

Originality/value

This overview provides a comprehensive summary of evidence examining the effects of meal timing and frequency on adult lipid profiles. The current low- or moderate-quality evidence could not support the recommendation of alteration of meal frequency as an alternative to conventional non-pharmacological treatments for dyslipidaemia.

Keywords

Acknowledgements

This manuscript is based on a published abstract for a conference (Chong et al., 2022).

Funding: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Conflict of interest: The authors declare that they have no conflict of interest.

Data availability: Data generated or analysed during this study are provided in full within the published article and its supplementary materials.

Author contributions: Alene Sze Jing Yong: Conceptualisation, Methodology, Formal analysis, Writing – Original Draft, Writing – Review & Editing; Rosamund Wei Xin Koo: Formal analysis, Writing – Original Draft; Choon Ming Ng: Writing – Review & Editing; Shaun Wen Huey Lee: Writing – Review & Editing; Siew Li Teoh: Conceptualisation, Methodology, Writing – Review & Editing, Supervision.

Citation

Yong, A.S.J., Koo, R.W.X., Ng, C.M., Lee, S.W.H. and Teoh, S.L. (2024), "Effect of meal timing and frequency on lipid profile in adults: an overview of systematic reviews and meta-analyses", Nutrition & Food Science, Vol. 54 No. 5, pp. 906-921. https://doi.org/10.1108/NFS-08-2023-0178

Publisher

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Emerald Publishing Limited

Copyright © 2024, Emerald Publishing Limited

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