Collagen formula with Chinese herbal medicine can improve skin condition and reduce inflammation: a double-blind, randomized, placebo-controlled trial

Abstract

Purpose

Population aging was a global trend, and the most obvious thing after aging was the change in skin appearance. Therefore, the active ingredients that delay skin aging were particularly noticed. Past studies had pointed out that Chinese herbal extracts can improve skin elasticity, reduce wrinkles and melanin precipitation. The purpose of this paper is to explore whether combining hydrolyzed collagen with Chinese herbal extracts can improve skin conditions and achieve anti-inflammatory effects.

Design/methodology/approach

Fifty subjects were randomly divided into collagen or placebo groups, and one bottle of collagen or placebo drink was used every day for four weeks, after which skin and inflammatory factors were tested.

Findings

In comparison with the baseline results, the skin parameters were improving after four-week intervention. In addition, the IL-6, IL-8, TNF-a were significantly decreased and tissue inhibitor matrix metalloproteinase 1 (TIMP-1) was increased after four-week hydrolyzed collagen intervention.

Originality/value

This study showed that hydrolyzed collagen combined with Chinese herbal extracts can improve the condition of the skin, and can also reduce inflammatory associated factors, thereby achieving anti-aging effects.

Citation

Chang, H.-C., Lin, Y.-K., Liang, C.-H., Huang, H.-W., Lin, Y.-H., Lin, Y.-H., Hu, W.-C. and Chiang, C.F. (2021), "Collagen formula with Chinese herbal medicine can improve skin condition and reduce inflammation: a double-blind, randomized, placebo-controlled trial", Nutrition & Food Science, Vol. 51 No. 8, pp. 1236-1244. https://doi.org/10.1108/NFS-02-2021-0065